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pentobarbital will boost the stage or influence of ivosidenib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of ivosidenib with robust CYP3A4 inducers decreased ivosidenib plasma concentrations.pentobarbital will minimize the level or influence of celecoxib by affecting hepatic enzyme CYP2C

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